Professor Auguste Piccard was the inspiration for Professor Cuthbert Calculus in The Adventures of Tintin by Belgian cartoonist Hergé. Piccard held a teaching appointment in Brussels where Hergé spotted his unmistakable figure in the street. Piccard gained worldwide acclaim when he pierced the stratosphere twice in a balloon.
The movie starts off with Tintin and his dog Snowy browsing a European market. Tintin is having his portrait painted, and when the painting is revealed, it is the Tintin we are all used to seeing being held up by a digitally animated modern Tintin. I was pleasantly surprised by this reference.