"Rosie" "Rosemary" Rose Marie Kennedy (1918–2005). Known as "Rosemary" or "Rosie", she was rendered incapable of intelligible speech or caring for herself by a prefrontal lobotomy at age 23 – a new neurosurgical technique of the time and requested by her father – that was intended to cure her increasing mood swings and make her more manageable. The operation instead reduced her to an infantile state. From 1949, she lived in a residential care facility in Jefferson, Wisconsin until her death.
Amantine Lucile Aurore Dupin, best known by her pseudonym George Sand, was a remarkable woman - a prodigious novelist, dramatist and campaigner for all manner of political reform. A rebellious, cross-dressing, cigar-smoking, scandalously-acting woman writer who lived at a time that was certainly much more of a man's world than today. Chopin was only one of many famous men in her life. After the relationship fell apart, in 1847, he scarcely composed again, before his death two years later.